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|CAS Number:||1189805-46-6||Purity:||Mini 95%|
|Color:||Whit / Yellow / Blue / Red/ Green||Formula:||C11H15NO|
4 mmc replacement,
structurally similar to amphetamines, they contain a phenethylamine core featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain with an additional methyl substitution at Rα. Amphetamines and cathinones are alpha-methylated phenethylamines, cathinones contain an additional carbonyl group at R1. Mephedrone contains an additional methyl substitutions at RN, similarly to MDMA and methamphetamine, and R4 of its phenyl ring.
Given its chemical structure, mephedrone is likely to act as a releasing agent and a reuptake inhibitor for monoamine neurotransmitters such as dopamine, serotonin and noradrenaline.
Several articles published near the end of 2011 examined the effects of mephedrone in the brains of rats, as well as examining the reinforcing potential of mephedrone. Dopamine and serotonin were collected using microdialysis, and increases in dopamine and serotonin were measured.
dministration caused about a 500% increase in dopamine, and about a 950% increase in serotonin. They reached their peak concentrations at 40 minutes and 20 minutes and returned to baseline by 120 minutes after injection.
Analysis of the ratio for dopamine and serotonin indicated mephedrone was preferentially a serotonin releaser, with a ratio of 1.22:1 (serotonin vs. dopamine). Additionally, half-lives for the decrease in dopamine and serotonin were calculated and found to have decay rates of 24.5 minutes and 25.5 minutes.
These findings show mephedrone induces a massive increase in both dopamine and serotonin, combined with rapid clearance. This increase in neurotransmitters provides an explanation for the euphoric and stimulating subjective effects induced by this experience. The rapid rise and subsequent fall of dopamine levels could also explain some of the addictive properties of mephedrone display in some users.
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1. How is the quality?
The qualities of most products are above 99% purity, same are 99.7% purity.
2. How is the package?
Aluminum foil bag or as customer's required.
3. How is the storage?
Keep in dry and cool place.
4. Do I need to pay extra for shipping cost?
No, our price includes the shipping cost already; you need not pay for any tax and others.
5. Can I order sample to test?
Yes, you are welcome to order sample before placing bulk order. We will send the sample directly to your door by courier.
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