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|Biological Half-life:||3-6 Hours||Formula:||C18H27NO|
psychedelic research chemicals,
hallucinogenic research chemicals
3-MeO-PCP has a Ki of 20 nM for the dizocilpine (MK-801) site of the NMDA receptor, 216 nM for the serotonin transporter (SERT), and 42 nM for the sigma σ1 receptor. It does not bind to the norepinephrine or dopamine transporter nor to the sigma σ2 receptor (Ki >10,000 nM). Based on its structural similarity to 3-hydroxy-PCP (3-HO-PCP), which uniquely among arylcyclohexylamines has high affinity for the μ-opioid receptor in addition to the NMDA receptor, it was initially expected that 3-MeO-PCP would have opioid activity. However, radioligand binding assays with human proteins have shown that, contrary to common belief, the drug also does not interact with the μ-, δ-, or κ-opioid receptors at concentrations of up to 10,000 nM. As such, the notion that 3-MeO-PCP has opioid activity has been described as a myth.
ChemAxon published a topology analysis, which revealed an atom count of 28, bond count of 28, cyclomatic number of 1, chain atom count of 7, chain bond count of 7, asymmetric atom count of 1, and rotatable bond count of 3. Under geometry, the report revealed a dreiding energy equal to 31.87 kcal/mol with a volume equal to 181.62 Å3, a minimal projection area equal to 34.36 Å2 and maximum projection area equal to 57.93 Å2.
Other research showed compound to have a topological polar surface area of 29.1 A^2, a heavy atom count of 13, Isotope Atom Count of 0, Defined Atom Stereocenter Count of 0, Undefined Atom Stereocenter Count of 0, Defined Bond Stereocenter Count of 0, Undefined Bond Stereocenter Count of 0, and a Covalently-Bonded Unit Count of 1.
Mexedrone crystals is research chemicals and are intended for research purposes only in a controlled laboratory for scientific and forensic study and are NOT intended for human or animal consumption.
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