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U48800 Research Chemical Intermediates CAS 82657-23-6 Fomula C16H22Cl2N2O

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U48800 Research Chemical Intermediates CAS 82657-23-6 Fomula C16H22Cl2N2O

China U48800 Research Chemical Intermediates CAS 82657-23-6  Fomula C16H22Cl2N2O supplier

Large Image :  U48800 Research Chemical Intermediates CAS 82657-23-6 Fomula C16H22Cl2N2O

Product Details:

Place of Origin: China
Brand Name: DM
Certification: SGS
Model Number: 01

Payment & Shipping Terms:

Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: Aluminium foil bags and boxes; as your demand
Delivery Time: 1-2 days
Payment Terms: Western Union, MoneyGram,Bitocoin
Supply Ability: 500kg/month
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Detailed Product Description
Formula: C16H22Cl2N2O Other Names: U48800
Molar Mass: 329.27 G·mol−1 CAS: 82657-23-6
Purity: 98% Use: Chemical Intermediates Research

 

 

1. Quick details

 

Pro Name
 
U48800
CAS NO
 
82657-23-66
Molecular Formula
 
C16H22Cl2N2O
Appearance
 
White  powder
Delivery Time
 
Within 2 days after receive payment
PackAge
 
Aluminum foil bag
Port
 
Hongkong
Production Capacity
 
500 Kilogram/Month
Purity
 
99.5%
Storage
 
store in dry and cool place.
LimitNum
 
10 Gram
Application
 
For lab research
Color
 
White

2. Definitions

s an opioid analgesic drug developed by a team at Upjohn in the 1970s that acts as a selective agonist of the µ-opioid receptor with a Kd value of 5.3 nM compared to 910 nM for the κ-opioid receptor and has around 7.5 x the potency of morphine in animal models.

 

 is a structural isomer of the earlier opioid AH-7921  and the result of a great deal of work elucidating the quantitative structure–activity relationship of the scaffold.

 

Upjohn looked for the key moieties which gave the greatest activity[8] and posted over a dozen patents on related compounds, each optimizing one moiety] until they discovered that U-47700 was the most active.

 

ecame the lead compound of selective kappa-opioid receptor ligands such as U-50488, U-51754 (containing a single methylene spacer difference) and U-69,593, which share very similar structures. Although not used medically, the selective kappa ligands are used in research.

 

3. Pharmacology

The way in which opioids structurally mimic these natural endorphins results in their euphoria, pain relief and anxiolytic effects. This is because endorphins are responsible for reducing pain, causing sleepiness, and feelings of pleasure. They can be released in response to pain, strenuous exercise, orgasm, or general excitement.

 

may also be an agonist for the kappa-opioid receptor system. As a result of this, it has become the lead compound of selective kappa-opioid receptor ligands such as U-50488 and U-69,593, which share very similar structures. Its structure led to other chemists experimenting with it to see if rigid analogues would retain activity.  Although not used medically, the selective kappa ligands are used in research.

 

 

4. Company Introduction

Dongmao Biotechnology Co., Limited specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on.

 

Our products are produced on the basis of best technical team, advanced equipment, high qualified management which meets the requirements of security and environmental protection.

 

We earned customers' trust and created a good reputation during these years. we are committed to providing excellent quality products and the perfect service to friends all over the world.

 

We will provide the most comprehensive products and service to you!

We are looking forward to your cooperation.

 

5. superiority

 

1. Best quality in your requirement

2. Competitive price in China market

3. mature Technical support

4. Professional logistic support

5. Full experience of large numbers containers loading in Chinese sea port

6. Fast shipment by reputed shipping line

7. Packing with pallet as buyer's special request

8. Best service after shipment with email

9. Cargoes together with container after-sales service available

10. Full experience in export

11. Raw materials from Chinese origin

All we want is win-win business. Send yr. inquiries, you will get it!

 

6. Pictures

U48800 Research Chemical Intermediates CAS 82657-23-6  Fomula C16H22Cl2N2O

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