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|Compound Purity:||99.7%||Appearance:||Light Tan White Powder|
|IUPAC:||PAL-593, 3F-Phenmetrazine, 3F-Fenmetrazyna, 3'-fluorophenmetrazine||Application:||Research|
Strongest 3 FPM research chemical 3 - Fluorophenmetrazine CAS 8325122-12-1
3-Fluorophenmetrazine (also known as 3-FPM, 3-FPH and PAL-593) is a phenylmorpholine-based stimulant and fluorinated analogue of phenmetrazine that has been sold online as a designer drug.
3-FPM acts as a norepinephrine-dopamine releasing agent with EC50 values of 43 nM and 30 nM, respectively. It shows only negligible efficacy as a releaser of serotonin, with an EC50 value of 2558 nM.
Evaluation of its metabolic pathway revealed N‐oxidation, aryl hydroxylation and subsequent O‐methylation, alkyl hydroxylation, oxidation, and degradation of the ethyl‐bridge yielding the O/N‐bis‐dealkylated metabolite, combinations thereof and further glucuronidation or sulfations.
3-FPM is a new research chemical in the stimulant family with an IUPAC name of 2-(3-fluorophenyl)-3-methylmorpholine> 3'-fluorophenmetrazine. The chemical formula for 3-FPM is C11H14FNO and is has a molecular weight of 285.42g. 3-FPM is an analog of Phenmetrazine.
Research on Phenmetrazine was conducted by ACD/Labs’, US Environmental Protection Agency’s EPISuite, and ChemAxon. Properties that were predicted by ACD/Labs showed 2 #H bond acceptors, 1 #H bond donors, 1 #Freely rotating bonds, index of refraction at 1.503 with a surface tension of 34.4±3.0 dyne/cm, a flash point of 112.7±12.6 °C and a boiling point of 285.2±25.0 °C at 760 mmHg.
Properties that were predicted by the US Environmental Protection Agency’s EPISuite showed the boiling point at 281.69, melting point at 67.79, and the vapor pressure estimations at 0.00203. The report also showed water solubility at 25 deg C (mg/L): 3.073e+004. The removal in wastewater treatment was 1.97 percent for total removal, total biodegradation is 0.09 percent, total sludge adsorption is 1.88 percent, and to air 0.00.
Properties that were predicted by ChemAxon included a topology analysis, which showed an atom count of 28, bond count of 29, cyclomatic number of 2, chain atom count of 1, chain bond count of 2, asymmetric atom count of 2, and rotatable bond count of 1. Under geometry, the information provided showed dreiding energy of 31.14 kcal/mol with a volume of 177.45 Å3, a minimal projection area of 34.48 Å2 and maximum at 58.35 Å2.
Chemical and physical properties of Phenmetrazine include a heavy atom count of 13, topological polar surface area of 21.3 A2, covalently bonded unit count of 1, and an undefined atom stereocenter count of 2.
Molecular weight: 195.230
Compound purity: > 99.7%
Synonyms: PAL-593, 3F-Phenmetrazine, 3F-Fenmetrazyna, 3'-fluorophenmetrazine
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